Pathogenesis and Staging of Craniovertebral Tuberculosis: Radiographic Evaluation, Classification, and Natural History.

ABSTRACT:

Study design

Retrospective cohort.

Objective

To radiographically evaluate Craniovertebral junction (CVJ) tuberculosis infection pathogenesis and to propose a modification to the Lifeso classification.

Methods

A cohort of patients with radiologically or microbiologically identified CVJ tuberculosis treated at a single tertiary referral center in a TB endemic area was queried for characteristics about clinical presentation, treatment, and radiographic evidence of bone destruction and abscess formation were included. Disease was classified according to the Lifeso grading system and bony lesions were classified as either type 1 (preservation of underlying structure) or type 2 (damage of underlying structure).

Results

52 patients were identified (mean age 28.5 ± 13.

SUBMITTER: Chaudhary K 

PROVIDER: S-EPMC10538348 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature