Alcohol cue reactivity in the brain: Age-related differences in the role of social processes in addiction in male drinkers.

ABSTRACT: Social attunement (SA)-the tendency to harmonize behavior with the social environment-has been proposed to drive the escalation of alcohol use in adolescence, while reducing use in adulthood. Little is known about how heightened social sensitivity in adolescence may interact with neural alcohol cue reactivity-a marker of alcohol use disorder-and its relationship to alcohol use severity over time. The aims of this study were to test whether (1) adolescents and adults differ in social alcohol cue reactivity in the nucleus accumbens, anterior cingulate cortex, and right medial prefrontal cortex (mPFC), and (2) age moderates the relationship between social alcohol cue reactivity and social attunement, measures of drinking at baseline, and changes in drinking over time. A sample of male adolesc

SUBMITTER: Kuhns L 

PROVIDER: S-EPMC10538438 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature