Efficacy of citicoline as a supplement in glaucoma patients: A systematic review.

ABSTRACT:

Purpose

Glaucoma is a leading cause of irreversible blindness worldwide. Retinal ganglion cells (RGC), the neurons that connect the eyes to the brain, specifically die in glaucoma, leading to blindness. Elevated intraocular pressure (IOP) is the only modifiable risk factor, however, many patients progress despite excellent IOP control. Thus, alternative treatment strategies to prevent glaucoma progression are an unmet need. Citicoline has demonstrated neuroprotective properties in central neurodegenerative diseases. However, conclusive evidence of the effect of citicoline on glaucoma progression is missing. This systematic review investigates first-time the therapeutic potential of citicoline in glaucoma patients.

Methods

The present study was conducted according to the PRIS

SUBMITTER: Prinz J 

PROVIDER: S-EPMC10538785 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature