Single nucleotide polymorphisms and sickle cell disease-related pain: a systematic review.

ABSTRACT:

Background

Scientists have speculated genetic variants may contribute to an individual's unique pain experience. Although research exists regarding the relationship between single nucleotide polymorphisms and sickle cell disease-related pain, this literature has not been synthesized to help inform future precision health research for sickle cell disease-related pain. Our primary aim of this systematic review was to synthesize the current state of scientific literature regarding single nucleotide polymorphisms and their association with sickle cell disease-related pain.

Methods

Using the Prisma guidelines, we conducted our search between December 2021-April 2022. We searched PubMed, Web of Science, CINAHL, and Embase databases (1998-2022) and selected all peer-reviewed articl

SUBMITTER: Gehling GM 

PROVIDER: S-EPMC10538969 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature