Complications and mortality of Cushing's disease: report on data collected over a 20-year period at a referral centre.

ABSTRACT:

Context

Cushing's disease (CD) is rare condition burdened by several systemic complications correlated to higher mortality rates. The primary goal of clinicians is to achieve remission, but it is unclear if treatment can also increase life expectancy.

Aim

To assess the prevalence of cortisol-related complications and mortality in a large cohort of CD patients attending a single referral centre.

Materials and methods

The clinical charts of CD patients attending a referral hospital between 2001 and 2021 were reviewed.

Results

126 CD patients (median age at diagnosis 39 years) were included. At the last examination, 78/126 (61.9%) of the patients were in remission regardless of previous treatment strategies. Patients in remission showed a significant improvement i

SUBMITTER: Mondin A 

PROVIDER: S-EPMC10539191 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature