Recurrent cardiovascular events in patients with type 2 diabetes and haemodialysis: analysis from the 4D Study.

ABSTRACT:

Background

In the 'Die Deutsche Diabetes Dialyse Studie' (4D Study), treatment of patients with type 2 diabetes mellitus (T2DM) on haemodialysis (HD) with atorvastatin compared with placebo had no significant effect on the first composite primary major adverse cardiovascular event (MACE) endpoint of death from cardiac causes, fatal stroke, non-fatal myocardial infarction or non-fatal stroke. In this study we analysed first and recurrent events in 1255 patients from the 4D Study.

Methods

We conducted an event history analysis to investigate the effects of previous clinical events on the risk of different endpoints in the total patient group and after stratification by randomization group.

Results

During a median follow-up of 4 years, a total of 548 MACEs occurred, with

SUBMITTER: Marx N 

PROVIDER: S-EPMC10539202 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature