The coexistence of diabetic retinopathy and diabetic nephropathy is associated with worse kidney outcomes.

ABSTRACT:

Background

Up to 50-60% of patients with diabetes have non-diabetic kidney disease (NDKD) on kidney biopsy. Diabetic retinopathy (DR) is a microvascular complication of diabetes frequently associated with diabetic nephropathy (DN). The objective of the current study was to investigate the kidney outcomes and survival in patients with biopsy diagnoses of DN and NDKD according to the presence of DR.

Methods

We conducted an observational, multicentre and retrospective study of the pathological findings of renal biopsies from 832 consecutive patients with diabetes from 2002 to 2014 from 18 nephrology departments. The association of DR with kidney replacement therapy (KRT) or survival was assessed by Kaplan-Meier and Cox regression analyses.

Results

Of 832 patients with di

SUBMITTER: Bermejo S 

PROVIDER: S-EPMC10539224 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature