An MRI-based scoring system for pretreatment risk stratification in locally advanced rectal cancer.

ABSTRACT:

Background

Accurately assessing the risk of recurrence in patients with locally advanced rectal cancer (LARC) before treatment is important for the development of treatment strategies. The purpose of this study is to develop an MRI-based scoring system to predict the risk of recurrence in patients with LARC.

Methods

This was a multicenter observational study that enrolled participants who underwent neoadjuvant chemoradiotherapy. To evaluate the risk of recurrence in these patients, we developed the mrDEC scoring system and assessed inter-reader agreement. Additionally, we plotted Kaplan-Meier curves to compare the 3-year disease-free survival (DFS) and 5-year overall survival (OS) rates among patients with different mrDEC scores.

Results

A total of 1287 patients with

SUBMITTER: Zhao M 

PROVIDER: S-EPMC10539304 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature