Associations between anthropometric parameters and immune-phenotypical characteristics of circulating Tregs and serum cytokines.

ABSTRACT:

Objective

To investigate the associations between several anthropometric parameters and regulatory T cells (Tregs) and circulating cytokines in a population-based cohort.

Methods

Between 2018 and 2021, a total of 238 participants were examined up to three times within the scope of the MEGA study in Augsburg, Germany. Tregs were analyzed using flow cytometry and the serum concentrations of 52 cytokines were determined. Anthropometric parameters were measured, using also bioelectrical impedance analysis: body mass index (BMI), relative total body fat, relative visceral adipose tissue (rVAT), waist circumference (WC), waist-to-hip ratio (WHR) and body fat distribution. Associations were analyzed using linear mixed models with random intercept (Tregs) and conventional linear reg

SUBMITTER: Schmitz T 

PROVIDER: S-EPMC10539435 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature