De novo whole transcriptome analysis of Aeromonas hydrophila isolated from the gut of an infected Labeo rohita.

ABSTRACT: Aeromonas hydrophila is a major generalist bacterial pathogen causing severe infections and mortalities in aquatic animals. Its genome, which was the first to be sequenced from the Aeromonas genus, may serve as a model for studying pathogenic mechanisms. To explore the pathogen-host fitness mechanism of bacterium, a comprehensive comparative transcriptome ecotype analysis of A. hydrophila isolated from the gut of Labeo rohita during infection was performed. Special characteristics in gene expression, gene ontology terms and expression of pathogenesis-associated genes, including genes encoding secreted proteins, candidate effectors, hydrolases, and proteins involved in secondary metabolite production were revealed. Among the database, 6,533 were gene ontology (GO

SUBMITTER: Das BK 

PROVIDER: S-EPMC10539578 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature