First report of frequencies of Y chromosome microdeletions at a reproductive medicine center in Peru.

ABSTRACT:

Objective

Y chromosome Microdeletions are the second genetic cause of infertility in men. Despite its importance for infertility treatment, there is no previous research in Peru. The aim of this study was to determine the frequencies and characteristics of Y chromosome microdeletions in a group of men who sought infertility consultation at a specialized reproductive medicine center in Peru.

Methods

In this study, 201 semen samples were analyzed. The samples were obtained from Niu Vida's fertility program. Each seminal sample was analyzed according to the recommendations of the Laboratory Manual of the World Health Organization (WHO) 2010. A buccal swab and a 500 μL aliquot of seminal sample were used for the molecular study of Y chromosome microdeletions in each patient. The

SUBMITTER: Gavilan M 

PROVIDER: S-EPMC10539958 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature