Rapid Point-of-Care Identification of Aspergillus Species in Microbial Keratitis.

ABSTRACT:

Importance

Microbial keratitis (MK) is a common cause of unilateral visual impairment, blindness, and eye loss in low-income and middle-income countries. There is an urgent need to develop and implement rapid and simple point-of-care diagnostics for MK to increase the likelihood of good outcomes.

Objective

To evaluate the diagnostic performance of the Aspergillus-specific lateral-flow device (AspLFD) to identify Aspergillus species causing MK in corneal scrape and corneal swab samples of patients presenting with microbial keratitis.

Design, setting, and participants

This diagnostic study was conducted between May 2022 and January 2023 at the corneal clinic of Aravind Eye Hospital in Madurai, Tamil Nadu, India. All study participants were recruited during their first p

SUBMITTER: Gunasekaran R 

PROVIDER: S-EPMC10540059 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature