Effect of low-pressure pneumoperitoneum on pain and inflammation in laparoscopic cholecystectomy: a randomized controlled clinical trial.

ABSTRACT:

Objective

We aim to assess the effect of low-pressure pneumoperitoneum on post operative pain and ten of the known inflammatory markers.

Background

The standard of care pneumoperitoneum set pressure in laparoscopic cholecystectomy is set to 12-14 mmHg, but many societies advocate to operate at the lowest pressure allowing adequate exposure of the operative field. Many trials have described the benefits of operating at a low-pressure pneumoperitoneum in terms of lower post operative pain, and better hemodynamic stability. But only few describe the effects on inflammatory markers and cytokines.

Methods

A prospective, double-blinded, randomised, controlled clinical trial, including patients who underwent elective laparoscopic cholecystectomy. Patients randomised into low

SUBMITTER: Rashdan M 

PROVIDER: S-EPMC10540329 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature