Ontology highlight
ABSTRACT:
SUBMITTER: Chen Z
PROVIDER: S-EPMC10540345 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Chen Zigui Z Yan Xin X Miao Changfeng C Liu Longyang L Liu Su S Xia Ying Y Fang Weiyi W Zheng Dandan D Luo Qisheng Q
Cancer cell international 20230928 1
Myosin heavy chain 9 (MYH9) plays an important role in a number of diseases. Nevertheless, the function of MYH9 in glioma is unclear. The present research aimed to investigate the role of MYH9 in glioma and determine whether MYH9 is involved in the temozolomide chemoresistance of glioma cells. Our results showed that MYH9 increased the proliferation and temozolomide resistance of glioma cells. The mechanistic experiments showed that the binding of MYH9 to NAP1L1, a potential promoter of tumor pr ...[more]