Missing values and inconclusive results in diagnostic studies - A scoping review of methods.

ABSTRACT: Most diagnostic studies exclude missing values and inconclusive results from the analysis or apply simple methods resulting in biased accuracy estimates. This may be due to the lack of availability or awareness of appropriate methods. This scoping review aimed to provide an overview of strategies to handle missing values and inconclusive results in the reference standard or index test in diagnostic accuracy studies. Conducting a systematic literature search in MEDLINE, Cochrane Library, and Web of Science, we could identify many articles proposing methods for addressing missing values in the reference standard. There are also several articles describing methods regarding missing values or inconclusive results in the index test. The latter encompass imputation, frequentist and Bayesian like

SUBMITTER: Stahlmann K 

PROVIDER: S-EPMC10540494 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature