Alterations of erythropoiesis in Covid-19 patients: prevalence of positive Coombs tests and iron metabolism.

ABSTRACT:

Background

For more than 2 years medical practice has been dealing with the Covid-19 pandemic. Atypical symptoms, such as frostbites and acrosyndromes, have appeared, and autoimmune anemias (some of which with cold agglutinins) have been described.

Objectives

We planned to study the prevalence of positive direct Coombs tests (DCTs) and hemolytic autoimmune anemia in patients infected with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and its correlation with complications, and then investigate the impact of the infection on iron metabolism.

Design

This is an observational, cross-sectional, single-center, exploratory study.

Methods

We obtained Coombs tests in a population of 179 infected patients at the CHU of Liège. We then studied iron metabolis

SUBMITTER: Schmitz L 

PROVIDER: S-EPMC10540584 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature