Comparative effectiveness and safety of analgesic medicines for adults with acute non-specific low back pain: systematic review and network meta-analysis.

ABSTRACT:

Objective

To evaluate the comparative effectiveness and safety of analgesic medicines for acute non-specific low back pain.

Design

Systematic review and network meta-analysis.

Data sources

Medline, PubMed, Embase, CINAHL, CENTRAL, ClinicalTrials.gov, clinicialtrialsregister.eu, and World Health Organization's International Clinical Trials Registry Platform from database inception to 20 February 2022.

Eligibility criteria for study selection

Randomised controlled trials of analgesic medicines (eg, non-steroidal anti-inflammatory drugs, paracetamol, opioids, anti-convulsant drugs, skeletal muscle relaxants, or corticosteroids) compared with another analgesic medicine, placebo, or no treatment. Adults (≥18 years) who reported acute non-specific low back pain (for

SUBMITTER: Wewege MA 

PROVIDER: S-EPMC10540836 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature