Exposures to FD&C synthetic color additives from over-the-counter medications and vitamins in United States children and pregnant women.

ABSTRACT:

Background

Food and Drug Administration (FDA) Food Drug and Cosmetic (FD&C) synthetic color additives (SCAs) have been associated with attentional and behavioral problems in children. Efforts to quantify exposure have focused on foods, while the contribution of medications and supplements remains unknown.

Objective

To estimate exposures to SCAs in children (2-16 years) and pregnant women from intake of common over-the-counter (OTC) medications and vitamins.

Methods

We estimated single-day exposure (mg/kg/day) to FD&C SCAs based on measurements of 25 different products and recommended dosages on product labels. Exposures were compared to SCA exposure estimates from food we previously developed and acceptable daily intakes (ADIs) established by FDA and the World Health

SUBMITTER: Thilakaratne R 

PROVIDER: S-EPMC10541320 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature