Outcomes and time trends of acute respiratory distress syndrome patients with and without liver cirrhosis: an observational cohort.

ABSTRACT:

Background

In studies prior to lung-protective ventilation, liver cirrhosis in acute respiratory distress syndrome (ARDS) was associated with high mortality rates. Since patients with cirrhosis have been excluded from many trials on ARDS, their outcome when treated with lung-protective ventilation is unclear. The objectives were to assess whether cirrhosis is associated with mortality in ARDS and trends over time in mortality and severity.

Methods

We conducted a retrospective analysis of a prospective observational cohort conducted in a 20-bed tertiary ICU from October 2003 to December 2021. All consecutive adult critically ill patients with ARDS were included. ARDS was defined by the Berlin criteria. The primary outcome was 90 day mortality, assessed with Kaplan-Meier curve

SUBMITTER: Pensier J 

PROVIDER: S-EPMC10541379 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature