Conversion of the bronchial tree into a conforming electrode to ablate the lung nodule in a porcine model.

ABSTRACT:

Background

Radiofrequency ablation (RFA) is one of the treatment options for lung nodules. However, the need for exact delivery of the rigid metal electrode into the center of the target mass often leads to complications or suboptimal results. To overcome these limitations, a concept of conforming electrodes using a flexible material has been tested in this study.

Methods

A bronchoscopy-guided RFA (CAROL) under a temperature-controlled mode was tested in in-vivo and ex-vivo porcine lungs. Gallium-based liquid metal was used for turning the bronchial tree into temporary RF electrodes. A customized bronchoscopy-guided balloon-tipped guiding catheter (CAROL catheter) was used to make the procedure feasible under fluoroscopy imaging guidance. The computer simulation was also per

SUBMITTER: Shah IA 

PROVIDER: S-EPMC10541426 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature