The gap-free genome of mulberry elucidates the architecture and evolution of polycentric chromosomes.

ABSTRACT: Mulberry is a fundamental component of the global sericulture industry, and its positive impact on our health and the environment cannot be overstated. However, the mulberry reference genomes reported previously remained unassembled or unplaced sequences. Here, we report the assembly and analysis of the telomere-to-telomere gap-free reference genome of the mulberry species, Morus notabilis, which has emerged as an important reference in mulberry gene function research and genetic improvement. The mulberry gap-free reference genome produced here provides an unprecedented opportunity for us to study the structure and function of centromeres. Our results revealed that all mulberry centromeric regions share conserved centromeric satellite repeats with different copies. Strikingly, we fo

SUBMITTER: Ma B 

PROVIDER: S-EPMC10541557 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature