Parity and Risk of Dementia in Women: The Atherosclerosis Risk in Communities Study.

ABSTRACT: Objective: Reproductive factors, including parity, may contribute to dementia risk, due to hormonal, physiological, social, and demographic factors. We hypothesized that higher parity would be associated with increased dementia risk. Materials and Methods: We utilized data from the Atherosclerosis Risk in Communities (ARIC) community-based cohort study. Participants were recruited in 1987-1989 and followed through 2017. Participants, all born between 1921 and 1945, were from four U.S. communities in Forsyth County, NC; Jackson, MS; Minneapolis, MN; and Washington County, MD. We included all female participants seen at ARIC visit three or five for whom parity and dementia outcomes were available (N = 7,921). The primary exposure was self-reported number of

SUBMITTER: DiBiase RM 

PROVIDER: S-EPMC10541925 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature