Group comparisons of the individual electroretinogram time trajectories for the ascending limb of the b-wave using a raw and registered time series.

ABSTRACT:

Objectives

The electroretinogram is a clinical test commonly used in the diagnosis of retinal disorders with the peak time and amplitude of the a- and b-waves used as the main indicators of retinal function. However, subtle changes that affect the shape of the electroretinogram waveform may occur in the early stages of disease or in conditions that have a neurodevelopmental or neurodegenerative origin. In such cases, we introduce a statistical approach to mathematically model the shape of the electroretinogram waveform that may aid clinicians and researchers using the electroretinogram or other biological signal recordings to identify morphological features in the waveforms that may not be captured by the time or time-frequency domains of the waveforms. We present a statistical gra

SUBMITTER: Brabec M 

PROVIDER: S-EPMC10542250 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature