The increased risk of colorectal cancer in the women who underwent hysterectomy from the South Korean National Health Insurance Database.

ABSTRACT:

Background

Several population-based studies and observational studies have shown that oophorectomy is associated with an increased risk of colorectal cancer (CRC), and hormone replacement therapy has been associated with a reduction in the risk of colorectal cancer. This study was carried out to investigate whether hysterectomy, which may affect the levels of female hormones, is associated with a risk of cancer of the specific gastrointestinal tract.

Methods

This population-based retrospective cohort study was conducted using insurance data provided by the Health Insurance Review and Assessment Service (HIRA) from January 1, 2007, to December 31, 2020. The hysterectomy group included 40- to 59-year-old women who underwent hysterectomy with uterine leiomyoma or uterine endome

SUBMITTER: Yuk J- 

PROVIDER: S-EPMC10542264 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature