Exploring the potential of Bacillus subtilis as cell factory for food ingredients and special chemicals.

ABSTRACT:

Background

Bacillus subtilis has been established as model microorganism for fundamental research in the laboratory on protein production/secretion and sporulation and as model bacterium for controlling spoilage in the food industry. It has also been used for production of (commercial) enzymes and several secondary metabolites such as vitamins. However, this doesn't fully reflect the potential of B. subtilis as a cell-factory. Here, various strains of B. subtilis, including food-grade, spore-deficient strains and industrially used strains, were compared for their growth and metabolic potential. Industry-relevant parameters were analyzed for all strains under various aeration regimes, under anaerobic conditions, in various nutritious and nutrient-limited cultivation media, with and

SUBMITTER: Chen T 

PROVIDER: S-EPMC10542680 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature