Visit-to-visit HbA1c variability is associated with poor prognosis in peritoneal dialysis patients with type 2 diabetes mellitus.

ABSTRACT:

Background

The prognosis of diabetic peritoneal dialysis patients is poor. HbA_1c serves as a crucial indicator for monitoring blood glucose control in patients with diabetes. Nevertheless, the relationship between visit-to-visit HbA_1c variability and prognosis in peritoneal dialysis with diabetes remains unclear.

Methods

All participants were categorized into 3 groups based on the HbA_1c variability score (HVS), which is the frequency of 0.5% (5.5 mmol/mol) alter in visit-to-visit HbA_1c values. Then, the hazard ratio to HVS with all-cause mortality was analyzed using the Cox hazard model, followed by the Fine-Gray competing risk model for major adverse cardiovascular events. Subgroup and sensitivity analysis were conducted to ascert

SUBMITTER: Zhang F 

PROVIDER: S-EPMC10542698 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature