Interactive effect of booster vaccination and vitamin D status on antibody production of Omicron variant-infected adults: A real-world cohort study.

ABSTRACT:

Introduction

Effect of booster vaccination and vitamin D status on antibody production of Omicron variant-infected adults need to be further explored.

Methods

A retrospective, longitudinal, real-world cohort study was performed. All included cases were divided into vitamin D deficiency (VDD) and non-VDD (control) groups according to baseline serum 25-hydroxyvitamin D [25(OH)D] concentration and then into unvaccinated, routinely vaccinated, and booster vaccinated VDD and control subgroups according to vaccination status. Antibody dynamics were observed within six time periods during hospitalization.

Results

A total of 204 adult cases were included, of which 121 (59%) were males; 23 (11%), 31 (15%), and 26 (13%) or 50 (25%), 35 (17%), and 39 (19%) were unvaccinated, rou

SUBMITTER: Peng D 

PROVIDER: S-EPMC10542990 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature