Targeted malaria elimination interventions reduce Plasmodium falciparum infections up to 3 kilometers away.

ABSTRACT: Malaria elimination interventions in low-transmission settings aim to extinguish hot spots and prevent transmission to nearby areas. In malaria elimination settings, the World Health Organization recommends reactive, focal interventions targeted to the area near malaria cases shortly after they are detected. A key question is whether these interventions reduce transmission to nearby uninfected or asymptomatic individuals who did not receive interventions. Here, we measured direct effects (among intervention recipients) and spillover effects (among non-recipients) of reactive, focal interventions delivered within 500m of confirmed malaria index cases in a cluster-randomized trial in Namibia. The trial delivered malaria chemoprevention (artemether lumefantrine) and vector control (indoor res

SUBMITTER: Benjamin-Chung J 

PROVIDER: S-EPMC10543053 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature