Evaluating antibiotic therapy for ventilator-associated pneumonia caused by gram-negative bacilli.

ABSTRACT:

Introduction

Ventilator-associated pneumonias (VAPs) are a complication of mechanical ventilation in the intensive care unit (ICU) that increase length of stay, morbidity, and mortality. While identifying and treating infections early is paramount to improving patient outcomes, more and more data demonstrate limited courses of antibiotics improve outcomes. Prolonged (10-14 day) courses of antibiotics have remained the standard of care for pneumonia due to gram-negative bacilli (GNR). We aimed to review our GNR VAPs to assess risk factors for recurrent GNR infections.

Methods

We reviewed trauma patients who developed VAP from 02/2019 through 05/2022. Demographics, injury characteristics, and outcomes were reviewed with a focus on pneumonia details including the cultured patho

SUBMITTER: Malhotra R 

PROVIDER: S-EPMC10543183 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature