Prenatal cannabis exposure is associated with localized brain differences that partially mediate associations with increased adolescent psychopathology.

ABSTRACT: Prenatal cannabis exposure (PCE) is associated with mental health problems, but the neurobiological mechanisms remain unknown. We find that PCE is associated with localized differences across neuroimaging metrics that longitudinally mediate associations with mental health in adolescence (n=9,322-10,186). Differences in brain development may contribute to PCE-related variability in adolescent mental health.

SUBMITTER: Baranger DA 

PROVIDER: S-EPMC10543205 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature