Transmission dynamics of SARS-CoV-2 variants in the Brazilian state of Para.

ABSTRACT:

Introduction

After three years since the beginning of the pandemic, the new coronavirus continues to raise several questions regarding its infectious process and host response. Several mutations occurred in different regions of the SARS-CoV-2 genome, such as in the spike gene, causing the emergence of variants of concern and interest (VOCs and VOIs), of which some present higher transmissibility and virulence, especially among patients with previous comorbidities. It is essential to understand its spread dynamics to prevent and control new biological threats that may occur in the future. In this population_based retrospective observational study, we generated data and used public databases to understand SARS-CoV-2 dynamics.

Methods

We sequenced 1,003 SARS-Co

SUBMITTER: Pinho CT 

PROVIDER: S-EPMC10543262 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature