Assessment of implementation methods in sepsis: study protocol for a cluster-randomized hybrid type 2 trial.

ABSTRACT:

Background

Sepsis is the leading cause of intensive care unit (ICU) admission and ICU death. In recognition of the burden of sepsis, the Surviving Sepsis Campaign (SSC) and the Institute for Healthcare Improvement developed sepsis "bundles" (goals to accomplish over a specific time period) to facilitate SSC guideline implementation in clinical practice. Using the SSC 3-h bundle as a base, the Centers for Medicare and Medicaid Services developed a 3-h sepsis bundle that has become the national standard for early management of sepsis. Emerging observational data, from an analysis conducted for the AIMS grant application, suggest there may be additional mortality benefit from even earlier implementation of the 3-h bundle, i.e., the 1-h bundle.

Method

The primary aims of this ra

SUBMITTER: Frank HE 

PROVIDER: S-EPMC10543317 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature