Risk of malignant disease in 1-year sepsis survivors, a registry-based nationwide follow-up study.

ABSTRACT:

Background

Cancer and sepsis share risk factors, and sepsis patients may have impaired immune response and increased morbidity long after intensive care. This study aimed to assess whether sepsis survivors are at increased risk for cancer. Our objective was to assess the incidence of new cancer in 1-year sepsis survivors and test the hypothesis that it is higher than that of the general population.

Methods

We obtained data on ICU admissions of adult patients from Swedish Intensive care registry (SICR) from 2005 to 2017. We included patients with an explicit ICD-10 code for sepsis for the primary ICU admission. We obtained data on cancer diagnoses (2001-2018), death (2005-2018) and emigration (2005-2018) from Cancer and Cause of death and National Patient Registry databases o

SUBMITTER: Hastbacka J 

PROVIDER: S-EPMC10543324 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature