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Case series of intestinal microsporidiosis in non-HIV patients caused by Encephalitozoon hellem.

ABSTRACT: Intestinal microsporidiosis is most often caused by Enterocytozoon bieneusi, and to a lesser extent by species of the genus Encephalitozoon. Until now, Encephalitozoon hellem was not clearly known to induce disease restricted to the intestine, or rarely in HIV subjects or in tropical countries. We report here 11 cases of delineated intestinal microsporidioses due to E. hellem diagnosed in France in non-HIV patients. Briefly, all patients were immunocompromised. They all suffered from diarrhoea, associated in nearly 50% of cases with weight loss. Concerning treatment, 5/11 patients had a discontinuation or a decrease of their immunosuppressive therapy, and 4/11 received albendazole. All patients recovered. Five different genotypes were identified based on the rRNA ITS sequence.

SUBMITTER: Nourrisson C

PROVIDER: S-EPMC10543343 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature

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Case series of intestinal microsporidiosis in non-HIV patients caused by Encephalitozoon hellem.

Nourrisson Céline C Hamane Samia S Bonhomme Julie J Durieux Marie-Fleur MF Foulquier Jean-Baptiste JB Lesthelle Sophie S Moniot Maxime M Bougnoux Marie-Elisabeth ME Poirier Philippe P

Emerging microbes & infections 20230914 2

Intestinal microsporidiosis is most often caused by Enterocytozoon bieneusi, and to a lesser extent by species of the genus Encephalitozoon. Until now, Encephalitozoon hellem was not clearly known to induce disease restricted to the intestine, or rarely in HIV subjects or in tropical countries. We report here 11 cases of delineated intestinal microsporidioses due to E. hellem diagnosed in France in non-HIV patients. Briefly, all patients were immunocompromised. They a ...[more]

PMID: 37706342

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