Disability and persistent motor deficits are linked to structural crossed cerebellar diaschisis in chronic stroke.

ABSTRACT: Brain imaging has significantly contributed to our understanding of the cerebellum being involved in recovery after non-cerebellar stroke. Due to its connections with supratentorial brain networks, acute stroke can alter the function and structure of the contralesional cerebellum, known as crossed cerebellar diaschisis (CCD). Data on the spatially precise distribution of structural CCD and their implications for persistent deficits after stroke are notably limited. In this cross-sectional study, structural MRI and clinical data were analyzed from 32 chronic stroke patients, at least 6 months after the event. We quantified lobule-specific contralesional atrophy, as a surrogate of structural CCD, in patients and healthy controls. Volumetric data were integrated with clinical scores of disabi

SUBMITTER: Guder S 

PROVIDER: S-EPMC10543354 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature