Friedewald formula may be used to calculate non-HDL-C from LDL-C and TG.

ABSTRACT:

Background

The Friedewald formula (FF) was originally designed 50 years ago and has been in use to this day despite better methods for estimating LDL cholesterol (LDL-C). Its success was mainly due to its simplicity. Nowadays most laboratories determine or can determine LDL-C by the direct method. The SCORE2 tables, recommended by the European Society of Cardiology, are based on non-HDL cholesterol (non-HDL-C). To calculate its value, one needs to know the values of total cholesterol (TC) and HDL-C. The presented idea is to use the FF to calculate non-HDL-C based on the values of LDL-C and TG instead of TC and HDL-C.

Methods and findings

Based on database of 26,914 laboratory results, covering the complete lipid panel, the error regarding non-HDL-C values calculated in both

SUBMITTER: Romaszko J 

PROVIDER: S-EPMC10543427 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature