Sinus inflammation and chronic rhinosinusitis are associated with a diagnosis of new onset asthma in the following year.

ABSTRACT:

Background

Chronic rhinosinusitis (CRS) and asthma commonly co-occur. No studies have leveraged large samples needed to formally address whether preexisting CRS is associated with new onset asthma over time.

Methods

We evaluated whether prevalent CRS [identified in two ways: validated text algorithm applied to sinus computerized tomography (CT) scan or two diagnoses] was associated with new onset adult asthma in the following year. We used electronic health record data from Geisinger from 2008 to 2019. For each year we removed persons with any evidence of asthma through the end of the year, then identified those with new diagnosis of asthma in the following year. Complementary log-log regression was used to adjust for confounding variables (e.g., sociodemographic, contact wi

SUBMITTER: Schwartz BS 

PROVIDER: S-EPMC10543467 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature