Small-angle scattering from flat bilayers containing correlated scattering length density inhomogeneities.

ABSTRACT: Model lipid bilayers have been widely employed as a minimal system to investigate the structural properties of biological membranes by small-angle X-ray (SAXS) and neutron scattering (SANS) techniques. These have nanometre resolution and can give information regarding membrane thickness and scattering length densities (SLDs) of polar and apolar regions. However, biological membranes are complex systems containing different lipids and protein species, in which lipid domains can be dynamically assembled and disassembled. Therefore, SLD variations can occur within the biomembrane. In this work, a novel method has been developed to simulate SAXS and SANS profiles obtained from large unilamellar vesicles containing SLD inhomogeneities that are spatially correlated over the membrane surface. Suc

SUBMITTER: Spinozzi F 

PROVIDER: S-EPMC10543680 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature