Pre-arterialization of coronary veins prior to retroperfusion of ischemic myocardium: percutaneous closure device.

ABSTRACT:

Background

Chronic coronary retroperfusion to treat myocardial ischemia has previously failed due to edema and hemorrhage of coronary veins suddenly exposed to arterial pressures. The objective of this study was to selectively adapt the coronary veins to become arterialized prior to coronary venous retroperfusion to avoid vascular edema and hemorrhage.

Methods and results

In 32 animals (Group I = 19 and Group II = 13), the left anterior descending (LAD) artery was occluded using an ameroid occlusion model. In Group I, the great cardiac vein was blocked with suture ligation (Group IA = 11) or with occlusion device (Group IB = 8) to arterialize the venous system within 2 weeks at intermediate pressure (between arterial and venous levels) before a coronary venous bypass graft (

SUBMITTER: Choy JS 

PROVIDER: S-EPMC10543752 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature