Culture-directed antibiotics in peritoneal dialysis solutions: a systematic review focused on stability and compatibility.

ABSTRACT:

Background

This systematic review summarises the stability of less commonly prescribed antibiotics in different peritoneal dialysis solutions that could be used for culture-directed therapy of peritonitis, which would be especially useful in regions with a high prevalence of multidrug antibiotic-resistant strains.

Methods

A literature search of Medline, Scopus, Embase and Google Scholar for articles published from inception to 25 January, 2023 was conducted. Only antibiotic stability studies conducted in vitro and not recently reviewed by So et al. were included. The main outcomes were chemical, physical, antimicrobial and microbial stability. This protocol was registered in PROSPERO (registration number CRD42023393366).

Results

We screened 1254 abstracts, and 28 arti

SUBMITTER: Ling CW 

PROVIDER: S-EPMC10543841 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature