Association of IL-17F Gene Polymorphism and Its Serum Level with SARS-CoV-2 Infection.

ABSTRACT:

Objective

Although multiple studies have addressed the clinical outcomes of coronavirus disease, little data exist regarding the defi- nition of immune and inflammatory profiles associated with this infection. Its clinical manifestations often worsen in association with hypercytokinemia (elevated interleukin 8 and interleukin 17). We conducted this research to elucidate the effect of interleukin 17 levels and interleukin 17F gene polymorphism on the severity and outcomes of coronavirus disease.

Material and methods

Ninety patients with confirmed coronavirus disease and 30 healthy controls were enrolled. Coronavirus disease cases were classified into nonsevere, severe, and critical according to the World Health Organization definition. Approximately 10 mL peripheral blood sam

SUBMITTER: Hendawy SR 

PROVIDER: S-EPMC10544435 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature