Diagnostic challenge of Creutzfeldt-Jakob disease in a patient with multimorbidity: a case-report.

ABSTRACT:

Background

Creutzfeldt-Jakob disease (CJD) is a rapidly progressive and ultimately fatal neurodegenerative condition caused by prions. The clinical symptoms of CJD vary with its subtype, and may include dementia, visual hallucinations, myoclonus, ataxia, (extra)pyramidal signs and akinetic mutism. In the early course of disease however, several clinical symptoms of CJD may mimic those of co-existing morbidities.

Case presentation

We report a male in his 60s with a history of situs inversus totalis and Churg Strauss syndrome, who presented with speech fluency disturbances, neuropsychiatric symptoms and allodynia, a few months after becoming a widower. Initially presumed a bereavement disorder along with a flare-up of Churg Strauss, his symptoms gradually worsened with apraxia

SUBMITTER: Yaqub A 

PROVIDER: S-EPMC10544493 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature