The association of trauma with self-reported flares and disease activity in systemic lupus erythematosus (SLE).

ABSTRACT:

Objectives

Trauma has been linked to incident SLE, but its relationship with SLE disease activity is unknown. This analysis examines associations between trauma exposures and patient-reported SLE disease activity and flares.

Methods

Data were from the California Lupus Epidemiology Study (CLUES). Flares were self-reported as any flare and, of those, flares accompanied by medical care (hospitalization or physician contact). The Systemic Lupus Activity Questionnaire (SLAQ) assessed disease activity. The Brief Trauma Questionnaire (BTQ) assessed all historical trauma exposures. The Adverse Childhood Experiences (ACEs) questionnaire was available for a subset. Multivariable regression analyses (n = 252) examined whether trauma exposure was associated with flares or SLAQ controlli

SUBMITTER: Katz P 

PROVIDER: S-EPMC10544732 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature