Extrusion-based 3D printing of osteoinductive scaffolds with a spongiosa-inspired structure.

ABSTRACT: Critical-sized bone defects resulting from trauma, inflammation, and tumor resections are individual in their size and shape. Implants for the treatment of such defects have to consider biomechanical and biomedical factors, as well as the individual conditions within the implantation site. In this context, 3D printing technologies offer new possibilities to design and produce patient-specific implants reflecting the outer shape and internal structure of the replaced bone tissue. The selection or modification of materials used in 3D printing enables the adaption of the implant, by enhancing the osteoinductive or biomechanical properties. In this study, scaffolds with bone spongiosa-inspired structure for extrusion-based 3D printing were generated. The computer aided design process resulted

SUBMITTER: Kuhl J 

PROVIDER: S-EPMC10544914 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature