The efficacy of different nimodipine administration route for treating subarachnoid hemorrhage: A network meta-analysis.

ABSTRACT:

Background

A systematic review and network meta-analysis (NMA) were conducted to explore the optimal administration route of nimodipine for treatment subarachnoid hemorrhage.

Methods

Electronic databases (Pubmed, Embase, Web of Science and Cochrane databases) were systematically searched to identify randomized controlled trials evaluating different administration route of nimodipine (intravenous and enteral) versus placebo for treatment subarachnoid hemorrhage. Outcomes included case fatality at 3 months, poor outcome measured at 3 months (defined as death, vegetative state, or severe disability), incidence of delayed cerebral ischemia (DCI), delayed ischemic neurological deficit. A random-effect Bayesian NMA was conducted for outcomes of interest, and results were presented

SUBMITTER: Lei G 

PROVIDER: S-EPMC10545353 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature