High-definition transcranial direct current stimulation modulates theta response during a Go-NoGo task in traumatic brain injury.

ABSTRACT:

Objective

High Definition transcranial Direct Current Stimulation (HD-tDCS) has been shown to improve cognitive performance in individuals with chronic traumatic brain injury (TBI), although electrophysiological mechanisms remain unclear.

Methods

Veterans with TBI underwent active anodal (N = 15) vs sham (N = 10) HD-tDCS targeting the pre-supplementary motor area (pre-SMA). A Go-NoGo task was conducted simultaneously with electroencephalography (EEG) at baseline and after intervention completion.

Results

We found increased theta event-related spectral perturbation (ERSP) and inter-trial phase coherence (ITPC) during Go in the frontal midline electrodes overlying the pre-SMA after active HD-tDCS intervention, but not after sham. We also found increased theta phase cohe

SUBMITTER: Chiang HS 

PROVIDER: S-EPMC10545365 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature