Reactions of Benzylboronate Nucleophiles.

ABSTRACT: This short review summarizes our laboratory's development of benzylboronic esters as nucleophiles. Activation of the benzylboronic ester is achieved by irreversible coordination of an alkyllithium Lewis base to form a nucleophilic benzylboronate. This boronate was found to react with aldehydes, imines, ketones and alkyl bromides. A copper catalyst was employed in reactions of the boronate with epoxides and aziridines.

SUBMITTER: Barker TJ 

PROVIDER: S-EPMC10545366 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature