Magnetic nanoparticles modified with a copper(i) complex as a novel and efficient reusable catalyst for A³ coupling leading to C-N bond formation.

ABSTRACT: Propargylamines are an important and valuable family of nitrogen-containing compounds with many applications in the fields of medical, industrial, and chemical processes. One-pot multicomponent A³ coupling reactions of aldehydes, amines, and alkynes in the presence of transition metals as catalysts is an efficient strategy for preparing propargylamines. In this study, we fabricated a novel magnetically reusable copper nanocatalyst [Fe₃O₄-BIm-Pyrim-CuI] through the immobilization of the copper(i) complex on the surface of the magnetic nanoparticles modified with benzimidazole-pyrimidine ligand and evaluated its catalytic activity in the preparation of propargylamines through one-pot multicomponent A³ coupling reactions of aldehydes, amines, and al

SUBMITTER: Li W 

PROVIDER: S-EPMC10545981 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature