Complete patient exposure during paediatric brain cancer treatment for photon and proton therapy techniques including imaging procedures.

ABSTRACT:

Background

In radiotherapy, especially when treating children, minimising exposure of healthy tissue can prevent the development of adverse outcomes, including second cancers. In this study we propose a validated Monte Carlo framework to evaluate the complete patient exposure during paediatric brain cancer treatment.

Materials and methods

Organ doses were calculated for treatment of a diffuse midline glioma (50.4 Gy with 1.8 Gy per fraction) on a 5-year-old anthropomorphic phantom with 3D-conformal radiotherapy, intensity modulated radiotherapy (IMRT), volumetric modulated arc therapy (VMAT) and intensity modulated pencil beam scanning (PBS) proton therapy. Doses from computed tomography (CT) for planning and on-board imaging for positioning (kV-cone beam CT and X-ray imagin

SUBMITTER: De Saint-Hubert M 

PROVIDER: S-EPMC10546320 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature