RECIST 1.1 Target Lesion Categorical Response in Metastatic Renal Cell Carcinoma: A Comparison of Conventional versus Volumetric Assessment.

ABSTRACT: Purpose To investigate Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) approximations of target lesion tumor burden by comparing categorical treatment response according to conventional RECIST versus actual tumor volume measurements of RECIST target lesions. Materials and Methods This is a retrospective cohort study of individuals with metastatic renal cell carcinoma enrolled in a clinical trial (from 2003 to 2017) and includes individuals who underwent baseline and at least one follow-up chest, abdominal, and pelvic CT study and with at least one target lesion. Target lesion volume was assessed by (a) V_model, a spherical model of conventional RECIST 1.1, which was extrapolated from RECIST diameter, and (b) V_actual, manually contour

SUBMITTER: Gong AJ 

PROVIDER: S-EPMC10546365 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature